One of the great things about Wireshark is the completely customizable interface. Users can change the layout, column settings, protocol decode options, add/remove buttons, change colors, add/remove filters, and more. There is a lot of documentation on how to even write new protocol dissectors. Due to its open source nature and the active development community, one can modify the code and/or participate in its official development. What this means is no two instances of a Wireshark install have to be the same.